Tag Archives: treatment

Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients

A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is … Continue reading 

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Neoadjuvant Chemotherapy: The Debate Continues

Two articles in the Journal of Clinical Oncology debate the use of neoadjuvant chemotherapy – chemo given before surgery – for ovarian cancer patients. Based on some studies, researchers conclude … Continue reading 

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Fat Cells in the Omentum Help Fuel Ovarian Cancer

A new study suggests that the “fatty apron” of cells found in the abdomen help ovarian cancer cells grow. This research could help provide direction for new targets in treatment. … Continue reading 

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Women with BRCA2 Mutation in Ovarian Tumors have Higher Surivival Rates

A recent study shows that women with ovarian cancer who have the BRCA2 mutation live longer than those with the BRCA1 mutation. Because the BRCA1 and BRCA2 mutations works slightly … Continue reading 

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Cost of Side Effects of Treatment Should Be Factored into Cost of Care

Often, the cost of care for a treatment does not include the cost of visitos to the provider or the cost of addressing side-effects. This calculation does not encompass the … Continue reading 

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JAAPA: When the Patient Asks – Can I be Screened for Ovarian Cancer

The JAAPA published a When the Patient Asks column on screening for ovarian cancer. WHO TO SCREEN High-risk women with a genetic mutation or strong family history should be screened. … Continue reading 

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Carbo/Paclitaxel v. Carbo/PLD as first line treatment for Ovarian Cancer

A recently study evaluated standard first line therapy – carboplatin plus paclitaxel – against carboplatin plus Doxil (PLD). This study of more than 800 women found that the use of … Continue reading 

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Interventions to prevent postoperative complications in women with ovarian cancer.

Women suspected of having ovarian cancer may have complications related to their surgeries. The most common complications, according to a recent studetn published in teh Clinical Journal of Oncology Nursing, … Continue reading 

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GSH reduces toxicity of cisplatin in women with ovarian cancer

A study published in 1997 showed that glutathione (GSH), a supplement, can reduce the toxicities of treatment with cisplatin for women with ovarian cancer. Read the abstract here

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FDA Clears ROMA Test (HE4+CA-125)

The FDA cleared the ROMA Algorithm, which uses the CA-125 and HE4 blood markers, to determine the likelihood that a pelvic mass is malignant. The test is a tool to help … Continue reading 

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Personalizing CA-125 Levels for Ovarian Cancer Screening

Two new papers published in Cancer Prevention Research suggests that personalizing CA-125 levels related to ovarian cancer are helpful. The article suggests that the provide a two percent false positive rate are … Continue reading 

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The Annals of Extreme Surgery (NYT)

The New York Times ran an op-ed about the lack of evidence supporting heated chemotherapy (HIPEC). The article stated that while this new treatment gives patients hope, the data is … Continue reading 

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