Tag Archives: treatment

Study Argues for Increased Use of PARP Inhibitors

A study from the Oregon Health & Science University suggests that women who have a recurrence of ovarian cancer would benefit from PARP inhibitors, now being tested in women with hereditary ovarian cancer. The study enrolled women with non-hereditary ovarian cancer, … Continue reading 

Posted in News | Also tagged , , , | Leave a comment

Chemotherapy Causes Changes in the Brain

According to MRI results, chemotherapy causes small changes to fibers that connect neurons in the brain. These are associated with a decline in cognitive function. Read an article about the study here

Posted in News | Also tagged , , , , | Leave a comment

Race, Insurance Status, Influence Treatment of Ovarian Cancer

A study of more than 47,000 women with ovarian cancer found that uninsured and Medicaid patients were less likely to receive the standard of care. Additionally, women who were African American, Hispanic or had more comorbidities or who were treated … Continue reading 

Posted in News | Also tagged , , , , , , | Leave a comment

Avastin Shown to Slow Tumor Growth; Not Prolong Life

Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver bullet, this is a gift that shouldn’t be overlooked,” said … Continue reading 

Posted in News | Also tagged , , , , , , | Leave a comment

PARP Inhibitor Olarparib Fails to Meet Trial Endpoints

AstraZeneca announced that it would not continue trials of olarparib in ovarian cancer due to the results of the Phase II trial. The company’s press release is available here

Posted in News | Also tagged , , , | Leave a comment

EU Approves Use of Avastin for Ovarian Cancer

The European Commission has approved the use of Avastin in women newly diagnosed with ovarian cancer. Read more on this topic here

Posted in News | Also tagged , , , | Leave a comment

Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients

A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is active in other types of tumors, including colorectal. Read the … Continue reading 

Posted in News | Also tagged , , , , , , | Leave a comment

Neoadjuvant Chemotherapy: The Debate Continues

Two articles in the Journal of Clinical Oncology debate the use of neoadjuvant chemotherapy – chemo given before surgery – for ovarian cancer patients. Based on some studies, researchers conclude that neoadjuvant chemotherapy may be the best option for some … Continue reading 

Posted in News | Also tagged , , | Leave a comment

Fat Cells in the Omentum Help Fuel Ovarian Cancer

A new study suggests that the “fatty apron” of cells found in the abdomen help ovarian cancer cells grow. This research could help provide direction for new targets in treatment. Read an article about the research here

Posted in News | Also tagged , | Leave a comment

Women with BRCA2 Mutation in Ovarian Tumors have Higher Surivival Rates

A recent study shows that women with ovarian cancer who have the BRCA2 mutation live longer than those with the BRCA1 mutation. Because the BRCA1 and BRCA2 mutations works slightly differently, they have a different effect on survival. The BRCA2 … Continue reading 

Posted in News | Also tagged , , , , , , | Leave a comment

Cost of Side Effects of Treatment Should Be Factored into Cost of Care

Often, the cost of care for a treatment does not include the cost of visitos to the provider or the cost of addressing side-effects. This calculation does not encompass the full cost of care for a new treatment regiment or … Continue reading 

Posted in News | Also tagged , | Leave a comment

JAAPA: When the Patient Asks – Can I be Screened for Ovarian Cancer

The JAAPA published a When the Patient Asks column on screening for ovarian cancer. WHO TO SCREEN High-risk women with a genetic mutation or strong family history should be screened. Routine transvaginal and pelvic ultrasonography with a CA-125 test may … Continue reading 

Posted in News | Also tagged , , , , | Leave a comment