Tag Archives: side effects
Many Cancer Patients Have Chronic Pain
Topotecan Weekly Versus Conventional 5-Day Schedule in Patients With Platinum-Resistant Ovarian Cancer: A Randomized Multicenter Phase II Trial of the North-Eastern German Society of Gynecological Oncology Ovarian Cancer Study Group
Purpose Weekly administration of topotecan (Tw) is less toxic and widely considered a better treatment option than conventional 5-day therapy (Tc) in women with platinum-resistant recurrent ovarian cancer. We conducted a randomized phase II trial (TOWER [Topotecan Weekly Versus Conventional … Continue reading
FDA approves opioid analgesic to help cancer patients manage pain
FDA approves opioid analgesic to help cancer patients manage pain Enrollment in REMS program required for health care professionals The U.S. Food and Drug Administration today approved Abstral (fentanyl) transmucosal tablets to manage breakthrough pain for adults with cancer. Fentanyl … Continue reading
Harms often surface years after cancer drug approval
Serious and sometimes life-threatening side effects often go unreported until years after cancer drugs have been approved, Canadian researchers said Monday. Within four years of approval, five of the 12 drugs they looked at had earned a “black box warning” … Continue reading
FDA approves Xgeva to help prevent cancer-related bone injury
The U.S. Food and Drug Administration approved Xgeva (denosumab) on Thursday to help prevent skeletal-related events (SREs) in patients with cancer that has spread (metastasized) and damaged the bone. Skeletal-related events include bone fractures from cancer and bone pain requiring … Continue reading
Cancer Patients’ Secondary Symptoms Need Attention: Study
Many with pain, depression also bothered by fatigue, nausea and dry mouth, experts say Many cancer patients with pain or depression also experience physical symptoms, such as fatigue, dry mouth and nausea, that can cause disability, a new study shows. … Continue reading
More painkillers needed for cancer patients-experts
Cancer patients, particularly in developing regions, are in dire need of painkillers and affordable drugs, experts said. “It’s shocking and shameful the number of people who suffer needlessly because of the lack of access to analgesics,” John Seffrin, chief executive … Continue reading
Collateral damage: toxic effects of targeted antiangiogenic therapies in ovarian cancer
First-line chemotherapy fails in more than 20% of patients with epithelial ovarian cancer and about 40—50% of women who respond to initial treatment relapse within 2 years. In the recurrent setting, second-line chemotherapeutic agents have a 15—20% response rate with … Continue reading
Is chemotherapy-induced neutropenia a prognostic factor in patients with ovarian cancer?
OBJECTIVE: This study sought to determine if relative neutropenia (RN) following six cycles of paclitaxel/carboplatin could serve as a prognostic factor in patients with ovarian cancer. DESIGN: A single institution, retrospective study. SETTING: Tertiary academic referral center, Seoul, Korea Population. … Continue reading
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Also tagged chemotherapy, quality of life, Research, science, treatment
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In Reporting Symptoms, Don’t Patients Know Best? (NYT)
About six years ago, my doctor gave me some samples of a drug to treat pain from an injury. I took it for a few days and then woke up one morning with a big red blister on my tongue. … Continue reading
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Also tagged clinical trials, quality of life, science, symptoms, treatment
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Chemotherapy-induced Peripheral Neuropathy (NCI)
It usually starts in the hands and/or feet and creeps up the arms and legs. Sometimes it feels like a tingling or numbness. Other times, it’s more of a shooting and/or burning pain or sensitivity to temperature. It can include … Continue reading












