Tag Archives: science

Study Argues for Increased Use of PARP Inhibitors

A study from the Oregon Health & Science University suggests that women who have a recurrence of ovarian cancer would benefit from PARP inhibitors, now being tested in women with hereditary ovarian cancer. The study enrolled women with non-hereditary ovarian cancer, … Continue reading 

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Avastin Shown to Slow Tumor Growth; Not Prolong Life

Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver bullet, this is a gift that shouldn’t be overlooked,” said … Continue reading 

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DICER Mutation Found in Numerous Rare Cancers, Including Ovarian

A recent article explores the link between a number of reproductive cancers, including ovarian, uterine and testicular cancers. These cancers all have mutations in the DICER gene, warping its function. The study can be found here An article about the … Continue reading 

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PARP Inhibitor Olarparib Fails to Meet Trial Endpoints

AstraZeneca announced that it would not continue trials of olarparib in ovarian cancer due to the results of the Phase II trial. The company’s press release is available here

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EU Approves Use of Avastin for Ovarian Cancer

The European Commission has approved the use of Avastin in women newly diagnosed with ovarian cancer. Read more on this topic here

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Bilateral Oophorectomy Associated With Higher Prevalence of Low Bone Mineral Density and Arthritis in Younger Women

A study presented at a breast cancer conference showed a link between lower bone density and removal of the ovaries. Women who had both ovaries removed before 45 years of age and who never used HRT had a lower BMD … Continue reading 

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Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients

A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is active in other types of tumors, including colorectal. Read the … Continue reading 

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Screening Study for Ovarian Cancer

A new study of 545 women with a family history of ovarian cancer were  provided annual screening with the CA-125 blood test and transvaginal ultrasound. This interval of testing with these tools did not find any early stage ovarian cancers. Read … Continue reading 

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HE4 May be Helpful in Screening

A study based on blood samples from more than 100 ovarian cancer patients and 700 women without ovarian cancer suggested that the HE4 might be useful to use for women whose CA-125 levels are rising. Read the study abstract here

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Fat Cells in the Omentum Help Fuel Ovarian Cancer

A new study suggests that the “fatty apron” of cells found in the abdomen help ovarian cancer cells grow. This research could help provide direction for new targets in treatment. Read an article about the research here

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IVF Raises Risk of Ovarian Cancer

A study of 25,000 women, 19,000 of whom received In-Vitro Fertilization (IVF) found that the women who underwent IVF had higher rates of ovarian cancer. The cases of ovarian cancer in women who had IVF were borderline tumors.  The women … Continue reading 

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The Pill Halves the Risk of Ovarian Cancer

A new study of more than 300,000 women, 878 of whom developed ovarian cancer over an almost 10 year period, showed that women who took oral contraceptives (The Pill) had almost half the rate of ovarian cancer as those who … Continue reading 

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