Tag Archives: Research

Olaparib shows improvement in PFS but not OS, Thus Far

Olaparib, a PARP inhibitor, showed an 3.6 month improvement in progression free survival (PFS) in women with platinum sensitive recurrent ovarian cancer. However, based on the interim analsis, there is … Continue reading 

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Studies Show Many Providers Think There is a Screening Test for Ovarian Cancer

Two studies released this week indicate that health care providers believe that the CA-125 and/or the transvaginal ultrasound are appropriate screening tests for ovarian cancer. There is no medical organization … Continue reading 

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Study Argues for Increased Use of PARP Inhibitors

A study from the Oregon Health & Science University suggests that women who have a recurrence of ovarian cancer would benefit from PARP inhibitors, now being tested in women with hereditary … Continue reading 

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Chemotherapy Causes Changes in the Brain

According to MRI results, chemotherapy causes small changes to fibers that connect neurons in the brain. These are associated with a decline in cognitive function. Read an article about the study … Continue reading 

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Race, Insurance Status, Influence Treatment of Ovarian Cancer

A study of more than 47,000 women with ovarian cancer found that uninsured and Medicaid patients were less likely to receive the standard of care. Additionally, women who were African … Continue reading 

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Avastin Shown to Slow Tumor Growth; Not Prolong Life

Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver … Continue reading 

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DICER Mutation Found in Numerous Rare Cancers, Including Ovarian

A recent article explores the link between a number of reproductive cancers, including ovarian, uterine and testicular cancers. These cancers all have mutations in the DICER gene, warping its function. … Continue reading 

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PARP Inhibitor Olarparib Fails to Meet Trial Endpoints

AstraZeneca announced that it would not continue trials of olarparib in ovarian cancer due to the results of the Phase II trial. The company’s press release is available here

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EU Approves Use of Avastin for Ovarian Cancer

The European Commission has approved the use of Avastin in women newly diagnosed with ovarian cancer. Read more on this topic here

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Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients

A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is … Continue reading 

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Screening Study for Ovarian Cancer

A new study of 545 women with a family history of ovarian cancer were  provided annual screening with the CA-125 blood test and transvaginal ultrasound. This interval of testing with … Continue reading 

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Women’s Sexuality Altered by Diagnosis of Ovarian Cancer

A small focus group of women with ovarian cancer indicated that “Regardless of age, women reported that ovarian cancer treatment had a detrimental impact on their sexuality and that the … Continue reading 

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