Tag Archives: recurrence
Race, Insurance Status, Influence Treatment of Ovarian Cancer
A study of more than 47,000 women with ovarian cancer found that uninsured and Medicaid patients were less likely to receive the standard of care. Additionally, women who were African American, Hispanic or had more comorbidities or who were treated … Continue reading
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Avastin Shown to Slow Tumor Growth; Not Prolong Life
Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver bullet, this is a gift that shouldn’t be overlooked,” said … Continue reading
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Bilateral Oophorectomy Associated With Higher Prevalence of Low Bone Mineral Density and Arthritis in Younger Women
A study presented at a breast cancer conference showed a link between lower bone density and removal of the ovaries. Women who had both ovaries removed before 45 years of age and who never used HRT had a lower BMD … Continue reading
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Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients
A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is active in other types of tumors, including colorectal. Read the … Continue reading
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Another Ovarian Cancer Vaccine Trial Approved
PAPR Inhibitors May Work Against More Ovarian Cancers
PAPR inhibitors, first used in trials for women with ovarian cancer who had a mutation in the BRCA1 or BRCA2 gene, are now being used in trials for women without these genetic mutations and showing some effect. In a recent … Continue reading
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Phase II Trial of Phenoxodial Complete
INTRODUCTION: Chemoresistance is a major limitation in the treatment of ovarian cancer. Phenoxodiol is a novel biomodulator capable of reversing chemoresistance in vitro and in vivo. In this study, we determined the safety and efficacy of intravenous phenoxodiol in combination … Continue reading
Girls with ovarian germ-cell tumors can safely skip chemotherapy unless disease recurs, new study suggests
Researchers from Dana-Farber/Children’s Hospital Cancer Center (DF/CHCC) have found that as many as 50 percent of young girls treated for germ-cell ovarian tumors might safely be spared chemotherapy using a “watch and wait” strategy to determine if the follow-up treatment … Continue reading
New Clues to Treating Ovarian Cancer Relapse
Starting chemotherapy when first signs reappear not especially effective, study finds New research finds that women with ovarian cancer relapse who start chemotherapy as soon as levels of a biomarker for the cancer rise don’t live significantly longer than women … Continue reading
Cancergazing? CA125 and post-treatment surveillance in advanced ovarian cancer.
Post-treatment surveillance of advanced ovarian cancer involves regular testing of asymptomatic patients using the CA125 test. This practice is based on a rationale that is not supported by evidence from clinical trials. This paper aims to stimulate critical reflection concerning … Continue reading
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Recurrent Ovarian Cancer: Use of Contrast-enhanced CT and PET/CT to Accurately Localize Tumor Recurrence and to Predict Patients’ Survival
Purpose: To compare accuracy and interobserver variability in the detection and localization of recurrent ovarian cancer with contrast material–enhanced (CE) computed tomography (CT) and positron emission tomography (PET)/CT and determine whether imaging findings can be used to predict survival. Materials … Continue reading
“Shielded” ovarian cancer cells may survive chemotherapy
Monday 28 June 2010 Cancer Research UK Press Release “SHIELDED” OVARIAN CANCER CELLS MAY SURVIVE CHEMOTHERAPY TO RE-GROW TUMOUR Cancer Research UK scientists have discovered certain ovarian tumour cells that are resistant to chemotherapy can survive a first round of … Continue reading
