Tag Archives: outcomes

New Study on BRCA Mutation in Women with Ovarian Cancer

A new study of 1,001 women with ovarian cancer found that 14% of them carried a BRCA1 or BRCA2 mutation. However, 44% of those women did not have a family … Continue reading 

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Harvard to Test End of Life Checklist for Cancer Patients

Up to 450 cancer patients, seen by 60 oncologists, will provide feedback on patient satisfaction and treatment choices over the next three years. The aim of the program is to … Continue reading 

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Drug Costs an Issue in Cancer Care

The costs of drugs is increasingly becoming an issue in cancer care. The balance of quality and cost raises the issue of cost effectiveness. More presentations at the recent ASCO … Continue reading 

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An Update on PARP Inhibitors

Development of PARP inhibitors, which appear to work best in women with BRCA mutations, has faced setbacks recently. An article reviews the data, good and bad, about PARP inhibitors. The … Continue reading 

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Removing Fallopian Tubes Reduces Risk of Ovarian Cancer

Based on data showing that removing a woman’s fallopian tubes removes her risk of developing ovarian cancer, doctors are now urging women who are having their tubes tied to have … Continue reading 

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Phase III Trial of Bevacizumab with Chemotherapy

A Phase III trial of bevacizumab (Avastin) with gemcitabine + carboplatin versus gemcitabine + carboplatin in women with ovarian cancer showed the bevacizumab arm to improve progression free survival (PFS). … Continue reading 

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Studies Show Many Providers Think There is a Screening Test for Ovarian Cancer

Two studies released this week indicate that health care providers believe that the CA-125 and/or the transvaginal ultrasound are appropriate screening tests for ovarian cancer. There is no medical organization … Continue reading 

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Ovarian Cancer Patients with BRCA Mutations May Fare Better than Non-Carriers

A large meta-analysis of studies on ovarian cancer survival shows that women with the BRCA mutations survive longer after diagnosed with ovarian cancer. The research team’s analysis showed that the … Continue reading 

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Avastin Shown to Slow Tumor Growth; Not Prolong Life

Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver … Continue reading 

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PARP Inhibitor Olarparib Fails to Meet Trial Endpoints

AstraZeneca announced that it would not continue trials of olarparib in ovarian cancer due to the results of the Phase II trial. The company’s press release is available here

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Bilateral Oophorectomy Associated With Higher Prevalence of Low Bone Mineral Density and Arthritis in Younger Women

A study presented at a breast cancer conference showed a link between lower bone density and removal of the ovaries. Women who had both ovaries removed before 45 years of … Continue reading 

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Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients

A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is … Continue reading 

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