Tag Archives: outcomes

Studies Show Many Providers Think There is a Screening Test for Ovarian Cancer

Two studies released this week indicate that health care providers believe that the CA-125 and/or the transvaginal ultrasound are appropriate screening tests for ovarian cancer. There is no medical organization that has endorsed the current tools as appropriate for screening. … Continue reading 

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Ovarian Cancer Patients with BRCA Mutations May Fare Better than Non-Carriers

A large meta-analysis of studies on ovarian cancer survival shows that women with the BRCA mutations survive longer after diagnosed with ovarian cancer. The research team’s analysis showed that the 5-year overall survival rate for ovarian cancer was 36 percent … Continue reading 

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Avastin Shown to Slow Tumor Growth; Not Prolong Life

Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver bullet, this is a gift that shouldn’t be overlooked,” said … Continue reading 

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PARP Inhibitor Olarparib Fails to Meet Trial Endpoints

AstraZeneca announced that it would not continue trials of olarparib in ovarian cancer due to the results of the Phase II trial. The company’s press release is available here

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Bilateral Oophorectomy Associated With Higher Prevalence of Low Bone Mineral Density and Arthritis in Younger Women

A study presented at a breast cancer conference showed a link between lower bone density and removal of the ovaries. Women who had both ovaries removed before 45 years of age and who never used HRT had a lower BMD … Continue reading 

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Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients

A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is active in other types of tumors, including colorectal. Read the … Continue reading 

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Screening Study for Ovarian Cancer

A new study of 545 women with a family history of ovarian cancer were  provided annual screening with the CA-125 blood test and transvaginal ultrasound. This interval of testing with these tools did not find any early stage ovarian cancers. Read … Continue reading 

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Neoadjuvant Chemotherapy: The Debate Continues

Two articles in the Journal of Clinical Oncology debate the use of neoadjuvant chemotherapy – chemo given before surgery – for ovarian cancer patients. Based on some studies, researchers conclude that neoadjuvant chemotherapy may be the best option for some … Continue reading 

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Women with BRCA2 Mutation in Ovarian Tumors have Higher Surivival Rates

A recent study shows that women with ovarian cancer who have the BRCA2 mutation live longer than those with the BRCA1 mutation. Because the BRCA1 and BRCA2 mutations works slightly differently, they have a different effect on survival. The BRCA2 … Continue reading 

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Ovarian Cancer a Mystery, Especially for Black Women

The Grio reports that African American women are not well represented in clincial trials related to ovarian cancer. The article discusses a new trial meant to explore the epidemiology of ovarian cancer in African American women. Read the full article … Continue reading 

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Carbo/Paclitaxel v. Carbo/PLD as first line treatment for Ovarian Cancer

A recently study evaluated standard first line therapy – carboplatin plus paclitaxel – against carboplatin plus Doxil (PLD). This study of more than 800 women found that the use of Doxil was not superior to standard therapy, although the women … Continue reading 

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Interventions to prevent postoperative complications in women with ovarian cancer.

Women suspected of having ovarian cancer may have complications related to their surgeries. The most common complications, according to a recent studetn published in teh Clinical Journal of Oncology Nursing, were wound infection, fever, nausea and vomiting. The full article … Continue reading 

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