Tag Archives: genetics
Blood Test May Spot Inherited Ovarian Cancer
Researchers are developing a blood test which they believe will be able to detect mutations in more than 20 genes that may play a role in developing ovarian cancer. The … Continue reading
FDA panel advises caution on personal genetic testing
An FDA advisory panel recommended that medical professionals be available to help patients undergoing personal, at-home, genetic testing. Doubts remain as to the usefulness of many of these tests, however … Continue reading
Improved survival in non-Ashkenazi Jewish ovarian cancer patients with BRCA1 and BRCA2 gene mutations
A new study shows that ovarian cancer patients who had the non-Askenazi Jewish BRCA mutation had longer Progression Free Surivival time and Overall Survival times than ovairan cancer patients who … Continue reading
‘Rogue gene’ discovery could brake cancers
Researchers have found that by blocking the activity of a certain gene, WWP2, cancer cells can be prevented from spreading. At this point, there is no drug that could inhibit … Continue reading
Genetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers (JNCI)
Background Germline mutations in the BRCA1 and BRCA2 genes are associated with increased risks of breast and ovarian cancers. Although several common variants have been associated with breast cancer susceptibility … Continue reading
Chemosensitivity and outcome of BRCA1- and BRCA2-associated ovarian cancer patients after first-line chemotherapy compared with sporadic ovarian cancer patients
Background: Because it is insufficiently clear whether BRCA-associated epithelial ovarian cancer (EOC) is more chemosensitive than sporadic EOC, we examined response to chemotherapy, progression-free survival (PFS) and overall survival (OS) … Continue reading
Ovarian Cancer Advances When Genes Are Silenced
There are many mechanisms that alter the activity of genes — direct changes to the DNA code like mutations and deletions, or changes that control when genes are switched on … Continue reading
Wide Genetic Testing for Lynch Syndrome Cost Effective
Widespread genetic testing for Lynch Syndrome appears to be a cost-effective strategy for identifying those at risk for colorectal and endometrial cancer, according to a report in Cancer Prevention Research, … Continue reading
Test selects the 60 per cent of women with inherited ovarian cancer who could benefit from ‘smart’ drug
Scientists have developed a new test to select which patients with ovarian cancer will benefit from new drugs called PARP inhibitors, according to research presented at the NCRI Cancer Conference … Continue reading
Family health history a powerful, underused tool
Make Grandma spill the beans: Uncovering all the diseases that lurk in your family tree can trump costly genetic testing in predicting what illnesses you and your children are likely … Continue reading
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U.S. Says Genes Should Not Be Eligible for Patent
Reversing a longstanding policy, the federal government said on Friday that human and other genes should not be eligible for patents because they are part of nature. The new position … Continue reading
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Preserving the Self: The Process of Decision Making About Hereditary Breast Cancer and Ovarian Cancer Risk Reduction
Women who carry BRCA1 or BRCA2 (BRCA1/2) gene mutations have up to an 88% lifetime risk of breast cancer and up to a 65% lifetime risk of ovarian cancer. Strategies … Continue reading
