Tag Archives: genetics

Supreme Court to Hear Gene Patent Case

The Supreme Court of the United States will hear arguments in a case seeking to invalidate the patents on the BRCA1 and BRCA2 mutations. The patent-holder, Myriad Laboratories, owns patents … Continue reading 

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TRICARE to cover BRCA test

Late last year, TRICARE – the health program for Uniformed Service members – released regulations to comply with existing federal guidelines. These regulations stated that TRICARE could not cover devices … Continue reading 

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When Less Is More – Editorial

The L.A. Times published an editorial July 29 summing up years of data showing that aggressively screening and treating people for cancer does not always benefit them. The editorial also … Continue reading 

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New Study on BRCA Mutation in Women with Ovarian Cancer

A new study of 1,001 women with ovarian cancer found that 14% of them carried a BRCA1 or BRCA2 mutation. However, 44% of those women did not have a family … Continue reading 

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An Update on PARP Inhibitors

Development of PARP inhibitors, which appear to work best in women with BRCA mutations, has faced setbacks recently. An article reviews the data, good and bad, about PARP inhibitors. The … Continue reading 

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Removing Fallopian Tubes Reduces Risk of Ovarian Cancer

Based on data showing that removing a woman’s fallopian tubes removes her risk of developing ovarian cancer, doctors are now urging women who are having their tubes tied to have … Continue reading 

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Decision Tool for women with BRCA Mutations Released

The Stanford Medicine Cancer Clinic has designed an online tool for women with a BRCA mutation. These genetic mutations increase a woman’s risk of developing breast and ovarian cancer. The … Continue reading 

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Olaparib shows improvement in PFS but not OS, Thus Far

Olaparib, a PARP inhibitor, showed an 3.6 month improvement in progression free survival (PFS) in women with platinum sensitive recurrent ovarian cancer. However, based on the interim analsis, there is … Continue reading 

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Studies Show Many Providers Think There is a Screening Test for Ovarian Cancer

Two studies released this week indicate that health care providers believe that the CA-125 and/or the transvaginal ultrasound are appropriate screening tests for ovarian cancer. There is no medical organization … Continue reading 

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Ovarian Cancer Patients with BRCA Mutations May Fare Better than Non-Carriers

A large meta-analysis of studies on ovarian cancer survival shows that women with the BRCA mutations survive longer after diagnosed with ovarian cancer. The research team’s analysis showed that the … Continue reading 

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Study Argues for Increased Use of PARP Inhibitors

A study from the Oregon Health & Science University suggests that women who have a recurrence of ovarian cancer would benefit from PARP inhibitors, now being tested in women with hereditary … Continue reading 

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DICER Mutation Found in Numerous Rare Cancers, Including Ovarian

A recent article explores the link between a number of reproductive cancers, including ovarian, uterine and testicular cancers. These cancers all have mutations in the DICER gene, warping its function. … Continue reading 

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