Tag Archives: early detection

Cancer victim wins suit

A jury of six in Waterbury Superior Court on Wednesday awarded $4 million to a New Milford woman and $1 million to her husband for negligence caused by her doctor for failing to recommend the removal of her ovaries before … Continue reading 

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Can a Multimarker Assay Improve Screening for Ovarian Cancer?

Almost three quarters of ovarian cancer cases are diagnosed at advanced stages, making this disease the most lethal gynecologic malignancy in U.S. women. Using sera from a total of 1400 healthy women, and women with early- and late-stage ovarian cancer, … Continue reading 

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Autoantibodies against stress-induced phosphoprotein-1 as a novel biomarker candidate for ovarian cancer.

Detection of autoantibodies against tumor-associated antigens (TAA) has recently been shown to be a powerful tool for early detection of various cancers. The aim of this study was to investigate the possibility of using autoantibodies against TAA as novel biomarkers … Continue reading 

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A Step Forward for Two-Step Screening for Ovarian Cancer

Stage for stage, ovarian cancers and breast cancers carry a similar prognosis—more than 90% of women diagnosed with stage I disease survive at least 5 years, but only 30% of women who present with distant disease are alive at 5 … Continue reading 

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Development of a Multimarker Assay for Early Detection of Ovarian Cancer

Purpose Early detection of ovarian cancer has great promise to improve clinical outcome. Patients and Methods Ninety-six serum biomarkers were analyzed in sera from healthy women and from patients with ovarian cancer, benign pelvic tumors, and breast, colorectal, and lung … Continue reading 

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Study Makes Strides in Understanding Ovarian Cancer

Findings may lead to development of screening tests for early detection New understanding about the early stages of ovarian cancer may lead to the development of a new screening test for the cancer, U.S. researchers say. In the study, scientists … Continue reading 

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Development of a Multimarker Assay for Early Detection of Ovarian Cancer (J.Clin Onc)

Purpose: Early detection of ovarian cancer has great promise to improve clinical outcome. Patients and Methods: Ninety-six serum biomarkers were analyzed in sera from healthy women and from patients with ovarian cancer, benign pelvic tumors, and breast, colorectal, and lung … Continue reading 

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p53 Autoantibodies as Potential Detection and Prognostic Biomarkers in Serous Ovarian Cancer

Background: This study examined the value of serum p53 autoantibodies (p53-AAb) as detection and prognostic biomarkers in ovarian cancer. Methods: p53-AAb were detected by ELISA in sera obtained preoperatively from women undergoing surgery for a pelvic mass. This group included … Continue reading 

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New frontiers for ovarian cancer risk evaluation: proteomics and contrast-enhanced ultrasound (AJR Am J Roentgenol)

OBJECTIVE: The grim ovarian cancer statistics are attributed to the fact that most women typically present with widespread disease at the time of initial diagnosis. Our current diagnostic tools, such as pelvic examination and standard ultrasound, are inadequate to detect … Continue reading 

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