Tag Archives: chemotherapy
Avastin Shown to Slow Tumor Growth; Not Prolong Life
Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver … Continue reading
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Also tagged clinical trials, outcomes, recurrence, Research, science, side effects, treatment
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EU Approves Use of Avastin for Ovarian Cancer
Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients
A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is … Continue reading
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Also tagged genetics, outcomes, recurrence, Research, resistance, science, treatment
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Neoadjuvant Chemotherapy: The Debate Continues
Two articles in the Journal of Clinical Oncology debate the use of neoadjuvant chemotherapy – chemo given before surgery – for ovarian cancer patients. Based on some studies, researchers conclude … Continue reading
Women with BRCA2 Mutation in Ovarian Tumors have Higher Surivival Rates
A recent study shows that women with ovarian cancer who have the BRCA2 mutation live longer than those with the BRCA1 mutation. Because the BRCA1 and BRCA2 mutations works slightly … Continue reading
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Also tagged cancer treatment, clinical trials, genetics, outcomes, Research, science, treatment
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The Annals of Extreme Surgery (NYT)
The New York Times ran an op-ed about the lack of evidence supporting heated chemotherapy (HIPEC). The article stated that while this new treatment gives patients hope, the data is … Continue reading
Chemo Dosing Influences Drug Resistance
A mouse study showed that continuous treatment with docetaxel (Taxotere) showed greater anti-tumor effects than treating the mice once a week or once every three weeks. Additionally, treating less often … Continue reading
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Also tagged cancer treatment, Research, resistance, science, treatment
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Chemotherapy Drug Shortages include Taxol
Drug shortages around the country are affecting cancer patients. Recently ABC news covered the paclitaxel (brand name: Taxol) shortage. Many cite the low cost of generic drugs as the cause of … Continue reading
Drug Combination to Treat Cancer Expected to Rise
According to an article in the Wall Street Journal, combinations of drugs to treat cancer will be used more frequently in the future. Many studies presented at the 2011 annual … Continue reading
J&J withdraws application with FDA for new ovarian cancer drug
Johnson & Johnson, the owner of rights to Yondelis in the United States, has withdrawn its New Drug Application with the Food and Drug Administration for approval of the drug … Continue reading
Cost-Effective Analysis of Bevacizumab for Ovarian Cancer
A study published in the Journal of Clinical Oncology concludes that “[t]he addition of bevacizumab to standard chemotherapy in patients with advanced ovarian cancer is not cost effective.” The study … Continue reading
Carbo/Doxil in elderly patients
BACKGROUND: CALYPSO (CAeLYx in Platinum Sensitive Ovarian) patients compared carboplatin-pegylated liposomal doxorubicin (C-PLD) with carboplatin-paclitaxel (C-P) in patients with late-relapsing recurrent ovarian cancer (ROC). We analyzed outcomes in patients <70 … Continue reading
