Tag Archives: chemotherapy
Chemotherapy Causes Changes in the Brain
According to MRI results, chemotherapy causes small changes to fibers that connect neurons in the brain. These are associated with a decline in cognitive function. Read an article about the study here
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Race, Insurance Status, Influence Treatment of Ovarian Cancer
A study of more than 47,000 women with ovarian cancer found that uninsured and Medicaid patients were less likely to receive the standard of care. Additionally, women who were African American, Hispanic or had more comorbidities or who were treated … Continue reading
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Avastin Shown to Slow Tumor Growth; Not Prolong Life
Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver bullet, this is a gift that shouldn’t be overlooked,” said … Continue reading
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EU Approves Use of Avastin for Ovarian Cancer
Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients
A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is active in other types of tumors, including colorectal. Read the … Continue reading
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Neoadjuvant Chemotherapy: The Debate Continues
Two articles in the Journal of Clinical Oncology debate the use of neoadjuvant chemotherapy – chemo given before surgery – for ovarian cancer patients. Based on some studies, researchers conclude that neoadjuvant chemotherapy may be the best option for some … Continue reading
Women with BRCA2 Mutation in Ovarian Tumors have Higher Surivival Rates
A recent study shows that women with ovarian cancer who have the BRCA2 mutation live longer than those with the BRCA1 mutation. Because the BRCA1 and BRCA2 mutations works slightly differently, they have a different effect on survival. The BRCA2 … Continue reading
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The Annals of Extreme Surgery (NYT)
The New York Times ran an op-ed about the lack of evidence supporting heated chemotherapy (HIPEC). The article stated that while this new treatment gives patients hope, the data is not clear that it provides benefit. HIPEC is given to … Continue reading
Chemo Dosing Influences Drug Resistance
A mouse study showed that continuous treatment with docetaxel (Taxotere) showed greater anti-tumor effects than treating the mice once a week or once every three weeks. Additionally, treating less often led to genetic changes that may lead to drug resistance. … Continue reading
Chemotherapy Drug Shortages include Taxol
Drug Combination to Treat Cancer Expected to Rise
According to an article in the Wall Street Journal, combinations of drugs to treat cancer will be used more frequently in the future. Many studies presented at the 2011 annual meeting of the American Society of Clinical Oncology explored the … Continue reading
J&J withdraws application with FDA for new ovarian cancer drug
Johnson & Johnson, the owner of rights to Yondelis in the United States, has withdrawn its New Drug Application with the Food and Drug Administration for approval of the drug to treat ovarian cancer. The drug is being used in … Continue reading
