Author Archives: Cara

Studies Show Many Providers Think There is a Screening Test for Ovarian Cancer

Two studies released this week indicate that health care providers believe that the CA-125 and/or the transvaginal ultrasound are appropriate screening tests for ovarian cancer. There is no medical organization that has endorsed the current tools as appropriate for screening. … Continue reading 

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Ovarian Cancer Patients with BRCA Mutations May Fare Better than Non-Carriers

A large meta-analysis of studies on ovarian cancer survival shows that women with the BRCA mutations survive longer after diagnosed with ovarian cancer. The research team’s analysis showed that the 5-year overall survival rate for ovarian cancer was 36 percent … Continue reading 

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Study Argues for Increased Use of PARP Inhibitors

A study from the Oregon Health & Science University suggests that women who have a recurrence of ovarian cancer would benefit from PARP inhibitors, now being tested in women with hereditary ovarian cancer. The study enrolled women with non-hereditary ovarian cancer, … Continue reading 

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Chemotherapy Causes Changes in the Brain

According to MRI results, chemotherapy causes small changes to fibers that connect neurons in the brain. These are associated with a decline in cognitive function. Read an article about the study here

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Race, Insurance Status, Influence Treatment of Ovarian Cancer

A study of more than 47,000 women with ovarian cancer found that uninsured and Medicaid patients were less likely to receive the standard of care. Additionally, women who were African American, Hispanic or had more comorbidities or who were treated … Continue reading 

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Avastin Shown to Slow Tumor Growth; Not Prolong Life

Two studies of the use of Avastin in ovarian cancer showed that the drug slowed tumor growth but did not improve overall survival. “While we are looking for that silver bullet, this is a gift that shouldn’t be overlooked,” said … Continue reading 

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DICER Mutation Found in Numerous Rare Cancers, Including Ovarian

A recent article explores the link between a number of reproductive cancers, including ovarian, uterine and testicular cancers. These cancers all have mutations in the DICER gene, warping its function. The study can be found here An article about the … Continue reading 

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PARP Inhibitor Olarparib Fails to Meet Trial Endpoints

AstraZeneca announced that it would not continue trials of olarparib in ovarian cancer due to the results of the Phase II trial. The company’s press release is available here

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EU Approves Use of Avastin for Ovarian Cancer

The European Commission has approved the use of Avastin in women newly diagnosed with ovarian cancer. Read more on this topic here

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Bilateral Oophorectomy Associated With Higher Prevalence of Low Bone Mineral Density and Arthritis in Younger Women

A study presented at a breast cancer conference showed a link between lower bone density and removal of the ovaries. Women who had both ovaries removed before 45 years of age and who never used HRT had a lower BMD … Continue reading 

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Mutation in KRAS Gene May Indicate Drug Resistance in Ovarian Cancer Patients

A genetic mutation that causes a change in the KRAS pathway appears to be linked to higher likelihood of platinum resistance in women with ovarian cancer. The KRAS pathway is active in other types of tumors, including colorectal. Read the … Continue reading 

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Screening Study for Ovarian Cancer

A new study of 545 women with a family history of ovarian cancer were  provided annual screening with the CA-125 blood test and transvaginal ultrasound. This interval of testing with these tools did not find any early stage ovarian cancers. Read … Continue reading 

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