Unrealistic Optimism in Early-Phase Oncology Trials

Posted:01/27/11

A new report questions the ethics of early stage oncology clinical trials, asserting that since patients have unrealistically high expectations of the outcomes of the trials, a question of informed consent is raised. 

According to the LA Times,

  • 60% were unrealistically optimistic that the drug being tested would control their cancer 
  • 63% were unrealistically optimistic that the experimental drug would improve their health in some way
  • 39% were unrealistically optimistic that they wouldn’t experience harmful side effects from the drugs in their trials

The abstract of the report is available here