Monthly Archives: August 2010
Survivors Teaching Students Update
Survivors Teaching Students: Saving Women’s LivesSM (STS) is one of Ovarian Cancer National Alliance’s flagship programs whereby we bring ovarian cancer survivors into the classrooms of nursing and medical students to share their personal stories and key information about the … Continue reading
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Evelyn Virginia MacMahon Ackerman (“Ginger”)
Evelyn Virginia MacMahon Ackerman passed away on July 30, 2010 after a 14-year battle with ovarian cancer. She was 71. Ginger, as she was known, daughter of Raymond C. and Bonnie F. MacMahon, was born in Wilmington, North Carolina on June … Continue reading
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Message from Annette Leal Mattern, President of the Board
I am greatly honored to be chosen to serve as President of the Board of Directors of the Ovarian Cancer National Alliance. It is an appointment that I accept with grave responsibility and great optimism. Most especially, I am encouraged … Continue reading
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Personalizing Therapy for Ovarian Cancer: BRCAness and Beyond
Although 70% to 80% of epithelial ovarian cancers respond to chemotherapy, less than 30% of patients can be cured with cytoreductive surgery combined with the best currently available drugs. Over the last three decades, the median survival for patients with … Continue reading
Gene Expression Profile of BRCAness That Correlates With Responsiveness to Chemotherapy and With Outcome in Patients With Epithelial Ovarian Cancer
Purpose To define a gene expression profile of BRCAness that correlates with chemotherapy response and outcome in epithelial ovarian cancer (EOC). Methods A publicly available microarray data set including 61 patients with EOC with either sporadic disease or BRCA germline … Continue reading
Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer
Purpose The prevalence of BRCA mutations in germline DNA from unselected ovarian cancer patients is 11% to 15.3%. It is important to determine the frequency of somatic BRCA changes, given the sensitivity of BRCA-mutated cancers to poly (ADP ribose) polymerase-1 … Continue reading
